Sequence Detail

ID/Version

P27786 (UniProt | EBI)

Last sequence update: 1992-08-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Steroid 17-alpha-hydroxylase/17,20 lyase; EC=1.14.14.19 {ECO:0000250|UniProtKB:P05093};AltName: Full=17-alpha-hydroxyprogesterone aldolase; EC=1.14.14.32 {ECO:0000250|UniProtKB:P05093};AltName: Full=CYPXVII;AltName: Full=Cyto

Provider

SWISS-PROT

Sequence

Polypeptide 507 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cyp17a1	cytochrome P450, family 17, subfamily a, polypeptide 1	31	148	4	8

Sequence references in MGI

J:11237 Youngblood GL, et al., Isolation, characterization, and chromosomal mapping of mouse P450 17 alpha-hydroxylase/C17-20 lyase. Genomics. 1991 May;10(1):270-5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:338155 Lee SG, et al., Hydroxylation and lyase reactions of steroids catalyzed by mouse cytochrome P450 17A1 (Cyp17a1). J Inorg Biochem. 2023 Mar;240:112085