ID/Version |
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Sequence description from provider |
RecName: Full=Septin-4 {ECO:0000312|MGI:MGI:1270156};AltName: Full=Bradeion beta {ECO:0000250|UniProtKB:O43236};AltName: Full=Brain protein H5 {ECO:0000303|PubMed:12581152};AltName: Full=CE5B3 beta {ECO:0000250|UniProtKB:O43236};AltName: Full=Cell divisio | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
478
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:15086
Kato K, A collection of cDNA clones with specific expression patterns in mouse brain. Eur J Neurosci. 1990;2(8):704-11
J:96669 Kissel H, et al., The Sept4 septin locus is required for sperm terminal differentiation in mice. Dev Cell. 2005 Mar;8(3):353-64 J:96670 Ihara M, et al., Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa. Dev Cell. 2005 Mar;8(3):343-52 J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:136786 Ihara M, et al., Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity. Neuron. 2007 Feb 15;53(4):519-33 J:144655 Sitz JH, et al., The Down syndrome candidate dual-specificity tyrosine phosphorylation-regulated kinase 1A phosphorylates the neurodegeneration-related septin 4. Neuroscience. 2008 Dec 2;157(3):596-605 J:165092 Garcia-Fernandez M, et al., Sept4/ARTS is required for stem cell apoptosis and tumor suppression. Genes Dev. 2010 Oct 15;24(20):2282-93 J:198601 Kim JB, et al., Identification of a novel anti-apoptotic E3 ubiquitin ligase that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC, HtrA2, and ARTS. J Biol Chem. 2013 Apr 26;288(17):12014-21 J:199466 Fuchs Y, et al., Sept4/ARTS regulates stem cell apoptosis and skin regeneration. Science. 2013 Jul 19;341(6143):286-9 J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22 J:269496 Koren E, et al., ARTS mediates apoptosis and regeneration of the intestinal stem cell niche. Nat Commun. 2018 Nov 2;9(1):4582 J:277914 Maruyama SY, et al., A critical role of solute carrier 22a14 in sperm motility and male fertility in mice. Sci Rep. 2016 Nov 4;6:36468 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 J:306638 Shinoda T, et al., Septin 14 is involved in cortical neuronal migration via interaction with Septin 4. Mol Biol Cell. 2010 Apr 15;21(8):1324-34 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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