Sequence Detail

ID/Version

P29268 Q922U0 G5E830 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=CCN family member 2;AltName: Full=Cellular communication network factor 2;AltName: Full=Connective tissue growth factor;AltName: Full=Hypertrophic chondrocyte-specific protein 24;AltName: Full=Protein FISP-12;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 348 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ccn2	cellular communication network factor 2	58	151	4	17

Sequence references in MGI

J:11407 Ryseck RP, et al., Structure, mapping, and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein. Cell Growth Differ. 1991 May;2(5):225-33
J:40574 Kireeva ML, et al., Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development. Exp Cell Res. 1997 May 25;233(1):63-77
J:53931 Babic AM, et al., Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo. Mol Cell Biol. 1999 Apr;19(4):2958-66
J:297327 Ohta K, et al., CCN2/CTGF binds the small leucine rich proteoglycan protein Tsukushi. J Cell Commun Signal. 2019 Mar;13(1):113-118