Sequence Detail

ID/Version

P29595 (UniProt | EBI)

Last sequence update: 1995-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=NEDD8;AltName: Full=Neddylin;AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 8; Short=NEDD-8;AltName: Full=Ubiquitin-like protein Nedd8;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 81 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nedd8	neural precursor cell expressed, developmentally down-regulated gene 8	30	107	4	35

Sequence references in MGI

J:1344 Kumar S, et al., Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem Biophys Res Commun. 1992 Jun 30;185(3):1155-61
J:44037 Kamitani T, et al., Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein. J Biol Chem. 1997 Nov 7;272(45):28557-62
J:72808 Tateishi K, et al., The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice. J Cell Biol. 2001 Nov 12;155(4):571-80
J:80189 Antenos M, et al., Interaction with Nedd8, a Ubiquitin-like Protein, Enhances the Transcriptional Activity of the Aryl Hydrocarbon Receptor. J Biol Chem. 2002 Nov 15;277(46):44028-34
J:90626 Carrabino S, et al., Expression pattern of the JAB1/CSN5 gene during murine embryogenesis: colocalization with NEDD8. Gene Expr Patterns. 2004 Jul;4(4):423-31
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89