Sequence Detail

ID/Version

P31041 Q6GSH7 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=T-cell-specific surface glycoprotein CD28;AltName: CD_antigen=CD28;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 218 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd28	CD28 antigen	56	96	3	22

Sequence references in MGI

J:11356 Harper K, et al., CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location. J Immunol. 1991 Aug 1;147(3):1037-44
J:14194 Shahinian A, et al., Differential T cell costimulatory requirements in CD28-deficient mice. Science. 1993 Jul 30;261(5121):609-12
J:23361 Gross JA, et al., The murine homologue of the T lymphocyte antigen CD28. Molecular cloning and cell surface expression. J Immunol. 1990 Apr 15;144(8):3201-10
J:260551 Dobbins J, et al., Binding of the cytoplasmic domain of CD28 to the plasma membrane inhibits Lck recruitment and signaling. Sci Signal. 2016 Jul 26;9(438):ra75