Sequence Detail

ID/Version

P31648 (UniProt | EBI)

Last sequence update: 2004-05-10
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Sodium- and chloride-dependent GABA transporter 1; Short=GAT-1;AltName: Full=Solute carrier family 6 member 1;

Provider

SWISS-PROT

Sequence

Polypeptide 599 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc6a1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	41	111	4	16

Sequence references in MGI

J:1492 Liu QR, et al., A family of genes encoding neurotransmitter transporters. Proc Natl Acad Sci U S A. 1992 Jul 15;89(14):6639-43
J:3704 Liu QR, et al., Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain [corrected] [published erratum appers in J Biol Chem 1993 Apr 25;268(12):9156]. J Biol Chem. 1993 Jan 25;268(3):2106-12
J:91892 McHugh EM, et al., The GABA transporter GAT1 and the MAGUK protein Pals1: interaction, uptake modulation, and coexpression in the brain. Mol Cell Neurosci. 2004 Jul;26(3):406-17
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:324192 Nishimura T, et al., Hypotaurine Is a Substrate of GABA Transporter Family Members GAT2/Slc6a13 and TAUT/Slc6a6. Biol Pharm Bull. 2018;41(10):1523-1529
J:324197 Krause S, et al., Identification and selective inhibition of the channel mode of the neuronal GABA transporter 1. Mol Pharmacol. 2005 Dec;68(6):1728-35