Sequence Detail

ID/Version

P32443 Q544T6 (UniProt | EBI)

Last sequence update: 1993-10-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Homeobox protein MOX-2 {ECO:0000303|PubMed:1363541};AltName: Full=Growth arrest-specific homeobox {ECO:0000303|PubMed:7623821};AltName: Full=Mesenchyme homeobox 2 {ECO:0000303|PubMed:1363541};

Provider

SWISS-PROT

Sequence

Polypeptide 303 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Meox2	mesenchyme homeobox 2	29	133	4	9

Sequence references in MGI

J:3682 Candia AF, et al., Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. Development. 1992 Dec;116(4):1123-36
J:27226 Andres V, et al., Regulation of Gax homeobox gene transcription by a combination of positive factors including myocyte-specific enhancer factor 2. Mol Cell Biol. 1995 Aug;15(8):4272-81
J:28894 Candia AF, et al., Amino acid sequence of Mox-2 and comparison to its Xenopus and rat homologs. Nucleic Acids Res. 1993 Oct 25;21(21):4982
J:56172 Mankoo BS, et al., Mox2 is a component of the genetic hierarchy controlling limb muscle development. Nature. 1999 Jul 1;400(6739):69-73
J:84754 Mankoo BS, et al., The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites. Development. 2003 Oct;130(19):4655-64
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:101703 Wu Z, et al., Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease. Nat Med. 2005 Sep;11(9):959-65
J:104217 Jin JZ, et al., Analysis of Meox-2 mutant mice reveals a novel postfusion-based cleft palate. Dev Dyn. 2006 Feb;235(2):539-46
J:234139 Coppiello G, et al., Meox2/Tcf15 heterodimers program the heart capillary endothelium for cardiac fatty acid uptake. Circulation. 2015 Mar 3;131(9):815-26