Sequence Detail

ID/Version

P34821 (UniProt | EBI)

Last sequence update: 1994-02-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Bone morphogenetic protein 8A; Short=BMP-8A;AltName: Full=Osteogenic protein 2; Short=OP-2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 399 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bmp8a	bone morphogenetic protein 8a	10	109	4	7

Sequence references in MGI

J:19593 Ozkaynak E, et al., Osteogenic protein-2. A new member of the transforming growth factor-beta superfamily expressed early in embryogenesis. J Biol Chem. 1992 Dec 15;267(35):25220-7
J:34634 Zhao GQ, et al., Evidence that mouse Bmp8a (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development. Mech Dev. 1996 Jul;57(2):159-68
J:46927 Zhao GQ, et al., Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis. Development. 1998 Mar;125(6):1103-12
J:172534 Kosa JP, et al., The protective role of bone morphogenetic protein-8 in the glucocorticoid-induced apoptosis on bone cells. Bone. 2011 May 1;48(5):1052-7
J:196276 Cheng H, et al., Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs). J Bone Joint Surg Am. 2003 Aug;85-A(8):1544-52