Sequence Detail

ID/Version

P35230 (UniProt | EBI)

Last sequence update: 1994-02-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Regenerating islet-derived protein 3-beta {ECO:0000305}; Short=REG-3-beta;AltName: Full=Pancreatitis-associated protein 1;AltName: Full=Regenerating islet-derived protein III-beta; Short=Reg III-beta;Contains: RecName: Full=

Provider

SWISS-PROT

Sequence

Polypeptide 175 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Reg3b	regenerating islet-derived 3 beta	29	102	3	12

Sequence references in MGI

J:4201 Itoh T, et al., Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP). Biochim Biophys Acta. 1993 Feb 20;1172(1-2):184-6
J:38547 Narushima Y, et al., Structure, chromosomal localization and expression of mouse genes encoding type III Reg, RegIII alpha, RegIII beta, RegIII gamma. Gene. 1997 Feb 7;185(2):159-68
J:182550 van Ampting MT, et al., Intestinally secreted C-type lectin Reg3b attenuates salmonellosis but not listeriosis in mice. Infect Immun. 2012 Mar;80(3):1115-20
J:196632 Stelter C, et al., Salmonella-induced mucosal lectin RegIIIbeta kills competing gut microbiota. PLoS One. 2011;6(6):e20749
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306415 Zhang H, et al., REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway. Commun Biol. 2021 Jun 7;4(1):688