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Sequence Detail
ID/Version
P35363 (UniProt | EBI) Last sequence update: 1994-06-01
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=5-hydroxytryptamine receptor 2A; Short=5-HT-2; Short=5-HT-2A;AltName: Full=Serotonin receptor 2A;
Provider SWISS-PROT
Sequence
Polypeptide 471 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Htr2a 5-hydroxytryptamine (serotonin) receptor 2A 114 110 4 16
Sequence references in MGI J:3194 Yang W, et al., Gene structure and expression of the mouse 5-HT2 receptor. J Neurosci Res. 1992 Oct;33(2):196-204
J:108058 Fiorica-Howells E, et al., 5-HT(2A) receptors: location and functional analysis in intestines of wild-type and 5-HT(2A) knockout mice. Am J Physiol Gastrointest Liver Physiol. 2002 May;282(5):G877-93
J:110958 Weisstaub NV, et al., Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. Science. 2006 Jul 28;313(5786):536-40
J:122935 Gonzalez-Maeso J, et al., Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior. Neuron. 2007 Feb 1;53(3):439-52
J:136808 Gonzalez-Maeso J, et al., Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature. 2008 Mar 6;452(7183):93-7
J:308957 Moreno JL, et al., Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A.mGlu2) receptor heteromerization and its psychoactive behavioral function. J Biol Chem. 2012 Dec 28;287(53):44301-19
J:333121 Becamel C, et al., The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins. J Biol Chem. 2004 May 7;279(19):20257-66

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory