Sequence Detail

ID/Version

P35846 Q9R222 (UniProt | EBI)

Last sequence update: 2013-12-11
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Folate receptor alpha; Short=FR-alpha;AltName: Full=Folate receptor 1;AltName: Full=Folate-binding protein 1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 255 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Folr1	folate receptor alpha	40	110	3	293

Sequence references in MGI

J:3362 Brigle KE, et al., Insertion of an intracisternal A particle within the 5'-regulatory region of a gene encoding folate-binding protein in L1210 leukemia cells in response to low folate selection. Association with increased protein expression. J Biol Chem. 1992 Nov 5;267(31):22351-5
J:11440 Brigle KE, et al., Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement. J Biol Chem. 1991 Sep 15;266(26):17243-9
J:54455 Bolton JA, et al., Retinoic acid-dependent upregulation of mouse folate receptor-alpha expression in embryonic stem cells, and conservation of alternative splicing patterns. Gene. 1999 Apr 16;230(2):215-24
J:57765 Piedrahita JA, et al., Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development. Nat Genet. 1999 Oct;23(2):228-32
J:84731 Tang LS, et al., Neural and orofacial defects in Folbp1 knockout mice. Birth Defects Res Part A Clin Mol Teratol. 2003 Apr;67(4):209-18
J:101924 Tang LS, et al., Developmental consequences of abnormal folate transport during murine heart morphogenesis. Birth Defects Res A Clin Mol Teratol. 2004 Jul;70(7):449-58
J:110064 Birn H, et al., Renal tubular reabsorption of folate mediated by folate binding protein 1. J Am Soc Nephrol. 2005 Mar;16(3):608-15
J:124492 Zhu H, et al., Cardiovascular abnormalities in Folr1 knockout mice and folate rescue. Birth Defects Res A Clin Mol Teratol. 2007 Apr;79(4):257-68
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89