Sequence Detail

ID/Version

P36895 (UniProt | EBI)

Last sequence update: 1994-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Bone morphogenetic protein receptor type-1A; Short=BMP type-1A receptor; Short=BMPR-1A; EC=2.7.11.30;AltName: Full=Activin receptor-like kinase 3; Short=ALK-3;AltName: Full=BMP-2/BMP-4 receptor;AltName: Full=S

Provider

SWISS-PROT

Sequence

Polypeptide 532 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bmpr1a	bone morphogenetic protein receptor, type 1A	149	146	4	89

Sequence references in MGI

J:19799 Koenig BB, et al., Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells. Mol Cell Biol. 1994 Sep;14(9):5961-74
J:23133 Suzuki A, et al., A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo [see comments]. Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10255-9
J:25936 Dewulf N, et al., Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis. Endocrinology. 1995 Jun;136(6):2652-63
J:202818 Degenkolbe E, et al., A GDF5 point mutation strikes twice--causing BDA1 and SYNS2. PLoS Genet. 2013 Oct;9(10):e1003846
J:213092 Wang SS, et al., Gdf6 induces commitment of pluripotent mesenchymal C3H10T1/2 cells to the adipocyte lineage. FEBS J. 2013 Jun;280(11):2644-51
J:268021 Li SF, et al., Downregulation of beta1,4-galactosyltransferase 5 improves insulin resistance by promoting adipocyte commitment and reducing inflammation. Cell Death Dis. 2018 Feb 7;9(2):196
J:335613 Wang CY, et al., Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type Ireceptor ALK3. Blood. 2020;135(6):453-456