Sequence Detail

ID/Version

P39061 Q60672 Q9JK63 Q9CRT2 Q62001 Q6P1Y4 Q61434 Q61437 Q6NZK9 Q8CCZ8 Q62002 (UniProt | EBI)

Last sequence update: 2007-05-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Collagen alpha-1(XVIII) chain {ECO:0000305};Contains: RecName: Full=Endostatin {ECO:0000305};Contains: RecName: Full=Non-collagenous domain 1 {ECO:0000305}; Short=NC1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1774 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Col18a1	collagen, type XVIII, alpha 1	28	133	4	164

Sequence references in MGI

J:15411 Abe N, et al., Identification of a novel collagen chain represented by extensive interruptions in the triple-helical region. Biochem Biophys Res Commun. 1993 Oct 29;196(2):576-82
J:18134 Oh SP, et al., Isolation and sequencing of cDNAs for proteins with multiple domains of Gly-Xaa-Yaa repeats identify a distinct family of collagenous proteins. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4229-33
J:18135 Rehn M, et al., Alpha 1(XVIII), a collagen chain with frequent interruptions in the collagenous sequence, a distinct tissue distribution, and homology with type XV collagen. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4234-8
J:18189 Rehn M, et al., Primary structure of the alpha 1 chain of mouse type XVIII collagen, partial structure of the corresponding gene, and comparison of the alpha 1(XVIII) chain with its homologue, the alpha 1(XV) collagen chain. J Biol Chem. 1994 May 13;269(19):13929-35
J:23590 Rehn M, et al., Identification of three N-terminal ends of type XVIII collagen chains and tissue-specific differences in the expression of the corresponding transcripts. The longest form contains a novel motif homologous to rat and Drosophila frizzled proteins. J Biol Chem. 1995 Mar 3;270(9):4705-11
J:31963 Rehn M, et al., Characterization of the mouse gene for the alpha 1 chain of type XVIII collagen (Col18a1) reveals that the three variant N-terminal polypeptide forms are transcribed from two widely separated promoters. Genomics. 1996 Mar 15;32(3):436-46
J:78145 Kim YM, et al., Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1. J Biol Chem. 2002 Aug 2;277(31):27872-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:289459 Felbor U, et al., Secreted cathepsin L generates endostatin from collagen XVIII. EMBO J. 2000 Mar 15;19(6):1187-94
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89