Sequence Detail

ID/Version

P39876 Q91WL9 (UniProt | EBI)

Last sequence update: 1995-02-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Metalloproteinase inhibitor 3;AltName: Full=Tissue inhibitor of metalloproteinases 3; Short=TIMP-3;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 211 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Timp3	tissue inhibitor of metalloproteinase 3	16	134	2	14

Sequence references in MGI

J:17020 Sun Y, et al., Molecular cloning of five messenger RNAs differentially expressed in preneoplastic or neoplastic JB6 mouse epidermal cells: one is homologous to human tissue inhibitor of metalloproteinases-3. Cancer Res. 1994 Mar 1;54(5):1139-44
J:17354 Leco KJ, et al., Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues. J Biol Chem. 1994 Mar 25;269(12):9352-60
J:19451 Apte SS, et al., Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP-3, is expressed in developing mouse epithelia, cartilage, and muscle, and is located on mouse chromosome 10. Dev Dyn. 1994 Jul;200(3):177-97
J:26093 Apte SS, et al., The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family. J Biol Chem. 1995 Jun 16;270(24):14313-8
J:28204 Sun Y, et al., Molecular cloning of mouse tissue inhibitor of metalloproteinases-3 and its promoter. Specific lack of expression in neoplastic JB6 cells may reflect altered gene methylation. J Biol Chem. 1995 Aug 18;270(33):19312-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89