Sequence Detail

ID/Version

P41047 Q9R1F2 Q61217 (UniProt | EBI)

Last sequence update: 1995-02-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Tumor necrosis factor ligand superfamily member 6;AltName: Full=CD95 ligand; Short=CD95-L;AltName: Full=Fas antigen ligand; Short=Fas ligand; Short=FasL;AltName: CD_antigen=CD178;Contains: RecName: Full=Tumor necrosi

Provider

SWISS-PROT

Sequence

Polypeptide 279 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fasl	Fas ligand	63	110	3	21

Sequence references in MGI

J:17445 Takahashi T, et al., Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell. 1994 Mar 25;76(6):969-76
J:21065 Lynch DH, et al., The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster. Immunity. 1994 May;1(2):131-6
J:28383 Peitsch MC, et al., Comparative molecular modelling of the Fas-ligand and other members of the TNF family. Mol Immunol. 1995 Jul;32(10):761-72
J:28840 Hahne M, et al., Characterization of the non-functional Fas ligand of gld mice. Int Immunol. 1995 Sep;7(9):1381-6
J:39809 Kayagaki N, et al., Polymorphism of murine Fas ligand that affects the biological activity. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3914-9
J:58362 Ayroldi E, et al., Cloning and expression of a short Fas ligand: A new alternatively spliced product of the mouse Fas ligand gene. Blood. 1999 Nov 15;94(10):3456-67
J:153501 O' Reilly LA, et al., Membrane-bound Fas ligand only is essential for Fas-induced apoptosis. Nature. 2009 Oct 1;461(7264):659-63