Sequence Detail

ID/Version

P43027 A2ARK2 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Growth/differentiation factor 5; Short=GDF-5;AltName: Full=Bone morphogenetic protein 14; Short=BMP-14;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 495 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gdf5	growth differentiation factor 5	50	148	3	19

Sequence references in MGI

J:17582 Storm EE, et al., Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily [see comments]. Nature. 1994 Apr 14;368(6472):639-43
J:88556 Oka C, et al., HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins. Development. 2004 Mar;131(5):1041-53
J:91306 Tocharus J, et al., Developmentally regulated expression of mouse HtrA3 and its role as an inhibitor of TGF-beta signaling. Dev Growth Differ. 2004 Jun;46(3):257-74
J:205290 Sartori R, et al., BMP signaling controls muscle mass. Nat Genet. 2013 Nov;45(11):1309-18