Sequence Detail

ID/Version

P43406 A2AKI6 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Integrin alpha-V;AltName: Full=Vitronectin receptor subunit alpha;AltName: CD_antigen=CD51;Contains: RecName: Full=Integrin alpha-V heavy chain;Contains: RecName: Full=Integrin alpha-V light chain;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1044 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Itgav	integrin alpha V	151	112	3	21

Sequence references in MGI

J:31981 Wada J, et al., Cloning of mouse integrin alphaV cDNA and role of the alphaV-related matrix receptors in metanephric development. J Cell Biol. 1996 Mar;132(6):1161-76
J:50951 Bader BL, et al., Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins. Cell. 1998 Nov 13;95(4):507-19
J:86753 Nakamura T, et al., Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature. 2002 Jan 10;415(6868):171-5
J:244456 Edwards JP, et al., Release of active TGF-beta1 from the latent TGF-beta1/GARP complex on T regulatory cells is mediated by integrin beta8. J Immunol. 2014 Sep 15;193(6):2843-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:296155 Castells MC, et al., gp49B1-alpha(v)beta3 interaction inhibits antigen-induced mast cell activation. Nat Immunol. 2001 May;2(5):436-42
J:313953 Fukao S, et al., gp49B-mediated negative regulation of antibody production by memory and marginal zone B cells. J Immunol. 2014 Jul 15;193(2):635-44
J:343322 Park S, et al., Tm4sf19 deficiency inhibits osteoclast multinucleation and prevents bone loss. Metabolism. 2023 Nov 26;151:155746