Sequence Detail

ID/Version

P46467 Q91W22 Q9R1C9 (UniProt | EBI)

Last sequence update: 2004-01-16
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Vacuolar protein sorting-associated protein 4B {ECO:0000305}; EC=3.6.4.6;AltName: Full=Suppressor of K(+) transport growth defect 1; Short=Protein SKD1;

Provider

SWISS-PROT

Sequence

Polypeptide 444 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Vps4b	vacuolar protein sorting 4B	83	97	3	10

Sequence references in MGI

J:20181 Perier F, et al., Identification of a novel mammalian member of the NSF/CDC48p/Pas1p/TBP-1 family through heterologous expression in yeast. FEBS Lett. 1994 Sep 5;351(2):286-90
J:56320 Scheuring S, et al., Cloning, characterisation, and functional expression of the Mus musculus SKD1 gene in yeast demonstrates that the mouse SKD1 and the yeast VPS4 genes are orthologues and involved in intracellular protein trafficking. Gene. 1999 Jun 24;234(1):149-59
J:60367 Bishop N, et al., ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking. Mol Biol Cell. 2000 Jan;11(1):227-39
J:62555 Yoshimori T, et al., The mouse SKD1, a homologue of yeast Vps4p, is required for normal endosomal trafficking and morphology in mammalian cells. Mol Biol Cell. 2000 Feb;11(2):747-63
J:82243 Beyer A, et al., Comparative sequence and expression analyses of four mammalian VPS4 genes. Gene. 2003 Feb 13;305(1):47-59
J:90848 Fujita H, et al., Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B. J Cell Sci. 2004 Jul 15;117(Pt 14):2997-3009
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89