Sequence Detail

ID/Version

P47713 (UniProt | EBI)

Last sequence update: 1996-02-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Cytosolic phospholipase A2; Short=cPLA2;AltName: Full=Phospholipase A2 group IVA;Includes: RecName: Full=Phospholipase A2; EC=3.1.1.4 {ECO:0000269|PubMed:1904318}; AltName: Full=Phosphatidylcholine 2-acylhydrolase;Include

Provider

SWISS-PROT

Sequence

Polypeptide 748 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)	86	100	4	13

Sequence references in MGI

J:39254 Uozumi N, et al., Role of cytosolic phospholipase A2 in allergic response and parturition. Nature. 1997 Dec 11;390(6660):618-22
J:39681 Bonventre JV, et al., Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2. Nature. 1997 Dec 11;390(6660):622-5
J:44936 Clark JD, et al., A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP. Cell. 1991 Jun 14;65(6):1043-51
J:107430 Marusic S, et al., Cytosolic phospholipase A2 alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis. J Exp Med. 2005 Sep 19;202(6):841-51
J:126304 Nagase T, et al., A pivotal role of cytosolic phospholipase A(2) in bleomycin-induced pulmonary fibrosis. Nat Med. 2002 May;8(5):480-4
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89