Sequence Detail

ID/Version

P48744 Q5CZY6 (UniProt | EBI)

Last sequence update: 1996-02-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Norrin;AltName: Full=Norrie disease protein homolog;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 131 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ndp	Norrie disease (pseudoglioma) (human)	90	102	3	9

Sequence references in MGI

J:30902 Berger W, et al., An animal model for Norrie disease (ND): gene targeting of the mouse ND gene. Hum Mol Genet. 1996 Jan;5(1):51-9
J:31799 Battinelli EM, et al., Characterization and mapping of the mouse NDP (Norrie disease) locus (Ndp). Mamm Genome. 1996 Feb;7(2):93-7
J:107732 Xu Q, et al., Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell. 2004 Mar 19;116(6):883-95
J:154863 Junge HJ, et al., TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling. Cell. 2009 Oct 16;139(2):299-311