Sequence Detail

ID/Version

P48758 Q91X28 (UniProt | EBI)

Last sequence update: 2007-04-17
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Carbonyl reductase [NADPH] 1 {ECO:0000305}; EC=1.1.1.184 {ECO:0000250|UniProtKB:P16152};AltName: Full=15-hydroxyprostaglandin dehydrogenase [NADP(+)]; EC=1.1.1.196 {ECO:0000250|UniProtKB:Q28960}; EC=1.1.1.197 {ECO:000

Provider

SWISS-PROT

Sequence

Polypeptide 277 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cbr1	carbonyl reductase 1	23	102	5	15

Sequence references in MGI

J:33127 Wei J, et al., Cloning a cDNA for carbonyl reductase (Cbr) from mouse cerebellum: murine genes that express cbr map to chromosomes 16 and 11. Genomics. 1996 15;34(1):147-8
J:256366 Morgan RA, et al., Carbonyl reductase 1 catalyzes 20beta-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity. Sci Rep. 2017 Sep 6;7(1):10633
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:304452 Bell R, et al., Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice. Mol Metab. 2021 Mar 27;:101225