Sequence Detail

ID/Version

P49722 Q6ZWV8 E9Q3A4 (UniProt | EBI)

Last sequence update: 2012-10-31
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Proteasome subunit alpha type-2;AltName: Full=Macropain subunit C3;AltName: Full=Multicatalytic endopeptidase complex subunit C3;AltName: Full=Proteasome component C3;

Provider

SWISS-PROT

Sequence

Polypeptide 234 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Psma2	proteasome subunit alpha 2	11	96	4	25

Sequence references in MGI

J:22468 Seelig A, et al., Characterization of mouse proteasome subunit MC3 and identification of proteasome subtypes with different cleavage characteristics. Proteasome subunits, proteasome subpopulations. Enzyme Protein. 1993;47(4-6):330-42
J:57232 Elenich LA, et al., The complete primary structure of mouse 20S proteasomes. Immunogenetics. 1999 Sep;49(10):835-42
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:107376 Khor B, et al., Proteasome activator PA200 is required for normal spermatogenesis. Mol Cell Biol. 2006 Apr;26(8):2999-3007
J:181547 Huber EM, et al., Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity. Cell. 2012 Feb 17;148(4):727-38
J:188902 Gomes AV, et al., Mapping the murine cardiac 26S proteasome complexes. Circ Res. 2006 Aug 18;99(4):362-71
J:196249 Lukic Z, et al., TRIM5alpha associates with proteasomal subunits in cells while in complex with HIV-1 virions. Retrovirology. 2011;8:93
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89