Sequence Detail

ID/Version

P50136 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial {ECO:0000250|UniProtKB:P12694}; EC=1.2.4.4 {ECO:0000250|UniProtKB:P12694};AltName: Full=Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain; Short=

Provider

SWISS-PROT

Sequence

Polypeptide 442 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bckdha	branched chain ketoacid dehydrogenase E1, alpha polypeptide	16	98	3	24

Sequence references in MGI

J:35117 Costeas PA, et al., Effects of insulin on the regulation of branched-chain alpha-keto acid dehydrogenase E1 alpha subunit gene expression. Biochem J. 1996 Aug 15;318(Pt 1):85-92
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89