Sequence Detail

ID/Version

P50516 Q3U777 Q8CHX2 Q3US31 Q3TKS0 Q3U5W3 Q3UDZ9 (UniProt | EBI)

Last sequence update: 2007-04-17
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=V-type proton ATPase catalytic subunit A; Short=V-ATPase subunit A; EC=7.1.2.2 {ECO:0000269|PubMed:23863464};AltName: Full=V-ATPase 69 kDa subunit;AltName: Full=Vacuolar proton pump subunit alpha;

Provider

SWISS-PROT

Sequence

Polypeptide 617 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	38	102	4	24

Sequence references in MGI

J:31176 Laitala-Leinonen T, et al., Resorption-cycle-dependent polarization of mRNAs for different subunits of V-ATPase in bone-resorbing osteoclasts. Mol Biol Cell. 1996 Jan;7(1):129-42
J:72557 Smith AN, et al., Molecular cloning and characterization of Atp6n1b: a novel fourth murine vacuolar H+-ATPase a-subunit gene. J Biol Chem. 2001 Nov 9;276(45):42382-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:187362 Munton RP, et al., Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics. 2007 Feb;6(2):283-93
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:304577 Alzamora R, et al., AMP-activated protein kinase regulates the vacuolar H+-ATPase via direct phosphorylation of the A subunit (ATP6V1A) in the kidney. Am J Physiol Renal Physiol. 2013 Oct 1;305(7):F943-56