Sequence Detail

ID/Version

P51150 (UniProt | EBI)

Last sequence update: 2004-04-13
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Ras-related protein Rab-7a; EC=3.6.5.2 {ECO:0000250|UniProtKB:P51149};

Provider

SWISS-PROT

Sequence

Polypeptide 207 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rab7	RAB7, member RAS oncogene family	100	106	3	180

Sequence references in MGI

J:30549 Vitelli R, et al., Cloning and expression analysis of the murine Rab7 cDNA. Biochim Biophys Acta. 1995 Dec 27;1264(3):268-70
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:163139 Mizuno K, et al., Rabring7, a novel Rab7 target protein with a RING finger motif. Mol Biol Cell. 2003 Sep;14(9):3741-52
J:206933 Farg MA, et al., C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking. Hum Mol Genet. 2014 Jul 1;23(13):3579-95
J:224803 Lizaso A, et al., beta-adrenergic receptor-stimulated lipolysis requires the RAB7-mediated autolysosomal lipid degradation. Autophagy. 2013 Aug;9(8):1228-43
J:235260 Kloer DP, et al., Assembly of the biogenesis of lysosome-related organelles complex-3 (BLOC-3) and its interaction with Rab9. J Biol Chem. 2010 Mar 5;285(10):7794-804
J:236517 Fujiwara T, et al., PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis. JCI Insight. 2016 Oct 20;1(17):e86330
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:345045 Fujita N, et al., Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy. Elife. 2017 Jan 7;6:e23367