Sequence Detail

ID/Version

P51906 O35869 O35875 Q6P1F7 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Excitatory amino acid transporter 3;AltName: Full=Excitatory amino-acid carrier 1 {ECO:0000303|PubMed:9233792};AltName: Full=Sodium-dependent glutamate/aspartate transporter 3;AltName: Full=Solute carrier family 1 member 1;

Provider

SWISS-PROT

Sequence

Polypeptide 523 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc1a1	solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1	179	108	3	9

Sequence references in MGI

J:25756 Mukainaka Y, et al., Molecular cloning of two glutamate transporter subtypes from mouse brain. Biochim Biophys Acta. 1995 May 11;1244(1):233-7
J:41613 Peghini P, et al., Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration. EMBO J. 1997 Jul 1;16(13):3822-32
J:78023 Butchbach ME, et al., Molecular cloning, gene structure, expression profile and functional characterization of the mouse glutamate transporter (EAAT3) interacting protein GTRAP3-18. Gene. 2002 Jun 12;292(1-2):81-90
J:143132 Akiduki S, et al., Modulation of the neural glutamate transporter EAAC1 by the addicsin-interacting protein ARL6IP1. J Biol Chem. 2008 Nov 14;283(46):31323-32
J:229937 Nagamori S, et al., Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):775-80
J:274779 Malik AR, et al., SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology. Cell Rep. 2019 Mar 5;26(10):2792-2804.e6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89