ID/Version |
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Sequence description from provider |
RecName: Full=Pyruvate kinase PKM; EC=2.7.1.40 {ECO:0000250|UniProtKB:P14618};AltName: Full=Pyruvate kinase muscle isozyme;AltName: Full=Threonine-protein kinase PKM2 {ECO:0000305}; EC=2.7.11.1 {ECO:0000250|UniProtKB:P14618};AltName: Full= | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
531
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:26187
Izumi S, et al., Molecular cloning of the complementary DNA for the mouse pyruvate kinase M-2 gene whose expression is dependent upon cell differentiation. Biochim Biophys Acta. 1995 Jun 20;1267(2-3):135-8
J:46540 de Luis O, et al., Gene expression of mouse M1 and M2 pyruvate kinase isoenzymes correlates with differential poly[A] tract extension of their mRNAs during the development of spermatogenesis. Biochim Biophys Acta. 1998 Mar 13;1396(3):294-305 J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:100999 Giannakopoulos NV, et al., Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. Biochem Biophys Res Commun. 2005 Oct 21;336(2):496-506 J:131445 Lee J, et al., Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription. Int J Biochem Cell Biol. 2008;40(5):1043-54 J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30 J:269368 Zhou HL, et al., Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury. Nature. 2019 Jan;565(7737):96-100 J:271270 Deng W, et al., The Circadian Clock Controls Immune Checkpoint Pathway in Sepsis. Cell Rep. 2018 Jul 10;24(2):366-378 J:277769 Simsek D, et al., The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity. Cell. 2017 Jun 1;169(6):1051-1065.e18 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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