Sequence Detail

ID/Version

P52946 Q3ZB03 (UniProt | EBI)

Last sequence update: 1996-10-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Pancreas/duodenum homeobox protein 1;AltName: Full=Insulin promoter factor 1; Short=IPF-1;AltName: Full=Islet/duodenum homeobox 1; Short=IDX-1;AltName: Full=Somatostatin-transactivating factor 1; Short=STF-1;

Provider

SWISS-PROT

Sequence

Polypeptide 284 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pdx1	pancreatic and duodenal homeobox 1	91	246	3	30

Sequence references in MGI

J:15273 Ohlsson H, et al., IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J. 1993 Nov;12(11):4251-9
J:79560 Nakae J, et al., Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nat Genet. 2002 Oct;32(2):245-53
J:89879 Liu A, et al., Identification of PCIF1, a POZ domain protein that inhibits PDX-1 (MODY4) transcriptional activity. Mol Cell Biol. 2004 May;24(10):4372-83
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116355 Liu Y, et al., DNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complex. J Biol Chem. 2001 May 25;276(21):17985-93