Sequence Detail

ID/Version

P56404 Q91XC2 (UniProt | EBI)

Last sequence update: 1998-07-15
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Aquaporin-8 {ECO:0000303|PubMed:10449905}; Short=AQP-8;

Provider

SWISS-PROT

Sequence

Polypeptide 261 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aqp8	aquaporin 8	70	132	5	7

Sequence references in MGI

J:44349 Ma T, et al., Cloning of a novel water and urea-permeable aquaporin from mouse expressed strongly in colon, placenta, liver, and heart. Biochem Biophys Res Commun. 1997 Nov 17;240(2):324-8
J:57303 Calamita G, et al., Cloning, structural organization and chromosomal localization of the mouse aquaporin-8 water channel gene (Aqp8). Cytogenet Cell Genet. 1999;85(3-4):237-41
J:104681 Yang B, et al., Phenotype analysis of aquaporin-8 null mice. Am J Physiol Cell Physiol. 2005 May;288(5):C1161-70
J:119872 Yang B, et al., Evidence from knockout mice against physiologically significant aquaporin 8-facilitated ammonia transport. Am J Physiol Cell Physiol. 2006 Sep;291(3):C417-23
J:243242 Bertolotti M, et al., AQP8 transports NOX2-generated H2O2 across the plasma membrane to promote signaling in B cells. J Leukoc Biol. 2016 Nov;100(5):1071-1079
J:323121 Su W, et al., Increased female fertility in aquaporin 8-deficient mice. IUBMB Life. 2010 Nov;62(11):852-7
J:331461 Liu K, et al., Purification and functional characterization of aquaporin-8. Biol Cell. 2006 Mar;98(3):153-61
J:331462 Ferri D, et al., Ontogeny, distribution, and possible functional implications of an unusual aquaporin, AQP8, in mouse liver. Hepatology. 2003 Oct;38(4):947-57
J:331969 Calamita G, et al., Expression and subcellular localization of the AQP8 and AQP1 water channels in the mouse gall-bladder epithelium. Biol Cell. 2005 Jun;97(6):415-23