Sequence Detail

ID/Version

P56485 Q91WI0 (UniProt | EBI)

Last sequence update: 2004-05-10
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Atypical chemokine receptor 3 {ECO:0000305};AltName: Full=C-X-C chemokine receptor type 7; Short=CXC-R7; Short=CXCR-7;AltName: Full=Chemokine orphan receptor 1;AltName: Full=G-protein coupled receptor RDC1 homolog; Sh

Provider

SWISS-PROT

Sequence

Polypeptide 362 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ackr3	atypical chemokine receptor 3	45	117	4	30

Sequence references in MGI

J:47562 Heesen M, et al., Cloning and chromosomal mapping of an orphan chemokine receptor: mouse RDC1. Immunogenetics. 1998 Apr;47(5):364-70
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:124566 Burns JM, et al., A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J Exp Med. 2006 Sep 4;203(9):2201-13
J:124878 Sierro F, et al., Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64
J:136246 Gerrits H, et al., Early postnatal lethality and cardiovascular defects in CXCR7-deficient mice. Genesis. 2008 May;46(5):235-45
J:167833 Yu S, et al., The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling. Dev Dyn. 2011 Feb;240(2):384-93
J:272319 Tiveron MC, et al., Expression and function of CXCR7 in the mouse forebrain. J Neuroimmunol. 2010;224(1-2):72-9
J:283877 Sanchez-Alcaniz JA, et al., Cxcr7 controls neuronal migration by regulating chemokine responsiveness. Neuron. 2011 Jan 13;69(1):77-90
J:286078 Whitman MC, et al., Decreased ACKR3 (CXCR7) function causes oculomotor synkinesis in mice and humans. Hum Mol Genet. 2019 Sep 15;28(18):3113-3125
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89