Sequence Detail

ID/Version

P56716 Q548Q8 (UniProt | EBI)

Last sequence update: 2002-06-06
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Oxygen-regulated protein 1;AltName: Full=Retinitis pigmentosa RP1 protein homolog;

Provider

SWISS-PROT

Sequence

Polypeptide 2095 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rp1	retinitis pigmentosa 1 (human)	30	99	2	9

Sequence references in MGI

J:55847 Pierce EA, et al., Mutations in a gene encoding a new oxygen-regulated photoreceptor protein cause dominant retinitis pigmentosa. Nat Genet. 1999 Jul;22(3):248-54
J:73803 Liu Q, et al., Identification and subcellular localization of the RP1 protein in human and mouse photoreceptors. Invest Ophthalmol Vis Sci. 2002 Jan;43(1):22-32
J:76071 Gao J, et al., Progressive photoreceptor degeneration, outer segment dysplasia, and rhodopsin mislocalization in mice with targeted disruption of the retinitis pigmentosa-1 (Rp1) gene. Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5698-703
J:85754 Liu Q, et al., RP1 is required for the correct stacking of outer segment discs. Invest Ophthalmol Vis Sci. 2003 Oct;44(10):4171-83
J:101744 Liu J, et al., Distinct gene expression profiles and reduced JNK signaling in retinitis pigmentosa caused by RP1 mutations. Hum Mol Genet. 2005 Oct 1;14(19):2945-58
J:109781 Liu Q, et al., The retinitis pigmentosa 1 protein is a photoreceptor microtubule-associated protein. J Neurosci. 2004 Jul 21;24(29):6427-36
J:151463 Yamashita T, et al., Essential and synergistic roles of RP1 and RP1L1 in rod photoreceptor axoneme and retinitis pigmentosa. J Neurosci. 2009 Aug 5;29(31):9748-60
J:178434 Omori Y, et al., Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22671-6