Sequence Detail

ID/Version

P57716 Q8VE20 E9QLZ6 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Nicastrin;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 708 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ncstn	nicastrin	97	103	3	29

Sequence references in MGI

J:64305 Yu G, et al., Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing [see comments]. Nature. 2000 Sep 7;407(6800):48-54
J:83376 Li T, et al., Nicastrin is required for assembly of presenilin/gamma-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals. J Neurosci. 2003 Apr 15;23(8):3272-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89