Sequence Detail

ID/Version

P58355 (UniProt | EBI)

Last sequence update: 2001-11-16
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Membrane-associated transporter protein;AltName: Full=Melanoma antigen AIM1; Short=Protein AIM-1;AltName: Full=Protein underwhite;AltName: Full=Solute carrier family 45 member 2;

Provider

SWISS-PROT

Sequence

Polypeptide 530 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc45a2	solute carrier family 45, member 2	21	100	3	26

Sequence references in MGI

J:72440 Newton JM, et al., Mutations in the Human Orthologue of the Mouse underwhite Gene (uw) Underlie a New Form of Oculocutaneous Albinism, OCA4. Am J Hum Genet. 2001 Nov;69(5):981-8
J:73518 Fukamachi S, et al., Mutations in the gene encoding B, a novel transporter protein, reduce melanin content in medaka. Nat Genet. 2001 Aug;28(4):381-5
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:217827 Bartolke R, et al., Proton-associated sucrose transport of mammalian solute carrier family 45: an analysis in Saccharomyces cerevisiae. Biochem J. 2014 Dec 1;464(2):193-201
J:328663 Liu Y, et al., Ablation of Proton/Glucose Exporter SLC45A2 Enhances Melanosomal Glycolysis to Inhibit Melanin Biosynthesis and Promote Melanoma Metastasis. J Invest Dermatol. 2022 Apr 23;