Sequence Detail

ID/Version

P59267 (UniProt | EBI)

Last sequence update: 2003-02-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Palmitoyltransferase ZDHHC2 {ECO:0000305}; EC=2.3.1.225 {ECO:0000269|PubMed:28167757};AltName: Full=Acyltransferase ZDHHC2 {ECO:0000305|PubMed:28167757}; EC=2.3.1.- {ECO:0000305|PubMed:28167757};AltName: Full=Zinc finger DHHC

Provider

SWISS-PROT

Sequence

Polypeptide 366 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Zdhhc2	zinc finger, DHHC domain containing 2	56	108	3	5

Sequence references in MGI

J:94875 Fukata M, et al., Identification of PSD-95 Palmitoylating Enzymes. Neuron. 2004 Dec 16;44(6):987-96
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:182957 Greaves J, et al., The palmitoyl transferase DHHC2 targets a dynamic membrane cycling pathway: regulation by a C-terminal domain. Mol Biol Cell. 2011 Jun 1;22(11):1887-95
J:284985 Woolfrey KM, et al., The palmitoyl acyltransferase DHHC2 regulates recycling endosome exocytosis and synaptic potentiation through palmitoylation of AKAP79/150. J Neurosci. 2015 Jan 14;35(2):442-56
J:285026 Jia L, et al., Gi/o signaling and the palmitoyltransferase DHHC2 regulate palmitate cycling and shuttling of RGS7 family-binding protein. J Biol Chem. 2011 Apr 15;286(15):13695-703
J:287027 Greaves J, et al., Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1365-E1374