Sequence Detail

ID/Version

P59598 (UniProt | EBI)

Last sequence update: 2003-04-23
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Polycomb group protein ASXL1;AltName: Full=Additional sex combs-like protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 1514 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Asxl1	ASXL transcriptional regulator 1	40	104	3	97

Sequence references in MGI

J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:114350 Cho YS, et al., Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor. J Biol Chem. 2006 Jun 30;281(26):17588-98
J:183204 Park UH, et al., Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}. J Biol Chem. 2011 Jan 14;286(2):1354-63
J:183214 Lee SW, et al., ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1. J Biol Chem. 2010 Jan 1;285(1):18-29
J:307674 Perez-Garcia V, et al., BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion. Elife. 2021 Jun 25;10:e63254