Sequence Detail

ID/Version

P60710 P99021 Q3TI89 Q64316 Q3TVP6 P02570 Q11211 Q6ZWM3 P70514 (UniProt | EBI)

Last sequence update: 1988-04-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Actin, cytoplasmic 1;AltName: Full=Beta-actin; EC=3.6.4.- {ECO:0000250|UniProtKB:P68137};Contains: RecName: Full=Actin, cytoplasmic 1, N-terminally processed;

Provider

SWISS-PROT

Sequence

Polypeptide 375 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Actb	actin, beta	146	125	4	57

Sequence references in MGI

J:8248 Tokunaga K, et al., Nucleotide sequence of a full-length cDNA for mouse cytoskeletal beta-actin mRNA. Nucleic Acids Res. 1986 Mar 25;14(6):2829
J:8272 Alonso S, et al., Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates. J Mol Evol. 1986;23(1):11-22
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100999 Giannakopoulos NV, et al., Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. Biochem Biophys Res Commun. 2005 Oct 21;336(2):496-506
J:177167 Tomsig JL, et al., Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif. J Biol Chem. 2003 Mar 21;278(12):10048-54
J:177986 Lin YH, et al., Identification and characterization of a novel Rab GTPase-activating protein in spermatids. Int J Androl. 2011 Oct;34(5 Pt 2):e358-67
J:201326 Lee BC, et al., MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation. Mol Cell. 2013 Aug 8;51(3):397-404
J:262339 Schmidt MV, et al., Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17213-8
J:265603 Baarlink C, et al., Nuclear actin network assembly by formins regulates the SRF coactivator MAL. Science. 2013 May 17;340(6134):864-7
J:270048 Wilkinson AW, et al., SETD3 is an actin histidine methyltransferase that prevents primary dystocia. Nature. 2019 Jan;565(7739):372-376
J:345440 Qi J, et al., Critical role of TPRN rings in the stereocilia for hearing. Mol Ther. 2024 Jan 3;32(1):204-217