Sequence Detail

ID/Version

P61014 P20006 Q3UQ75 (UniProt | EBI)

Last sequence update: 2004-04-26
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Phospholamban {ECO:0000303|PubMed:1394867, ECO:0000312|MGI:MGI:97622}; Short=PLB;

Provider

SWISS-PROT

Sequence

Polypeptide 52 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pln	phospholamban	71	115	3	17

Sequence references in MGI

J:3416 Ganim JR, et al., Mouse phospholamban gene expression during development in vivo and in vitro. Circ Res. 1992 Nov;71(5):1021-30
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:228307 Zhou T, et al., Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy. Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):15666-71
J:229305 Nelson BR, et al., A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle. Science. 2016 Jan 15;351(6270):271-5
J:260257 Anderson DM, et al., Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides. Sci Signal. 2016 Dec 6;9(457):ra119
J:272982 Niemeyer J, et al., The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban. EMBO Rep. 2019 Mar;20(3)
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:346446 Klocke B, et al., A novel role for phospholamban in the thalamic reticular nucleus. Sci Rep. 2024 Mar 16;14(1):6376
J:354399 Ha KN, et al., Tuning the structural coupling between the transmembrane and cytoplasmic domains of phospholamban to control sarcoplasmic reticulum Ca(2+)-ATPase (SERCA) function. J Muscle Res Cell Motil. 2012 Dec;33(6):485-92