Sequence Detail

ID/Version

P62192 Q03527 Q96AZ3 P49014 (UniProt | EBI)

Last sequence update: 2004-06-21
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=26S proteasome regulatory subunit 4; Short=P26s4;AltName: Full=26S proteasome AAA-ATPase subunit RPT2;AltName: Full=Proteasome 26S subunit ATPase 1;

Provider

SWISS-PROT

Sequence

Polypeptide 440 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Psmc1	protease (prosome, macropain) 26S subunit, ATPase 1	16	100	4	15

Sequence references in MGI

J:30881 Hoyle J, et al., Genomic organization and mapping of the mouse P26s4 ATPase gene: a member of the remarkably conserved AAA gene family. Genomics. 1996 Jan 1;31(1):115-8
J:73568 Park H, et al., Identification of proteins that interact with mammalian peptide:N-glycanase and implicate this hydrolase in the proteasome-dependent pathway for protein degradation. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11163-8
J:92605 Katiyar S, et al., A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins. Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13774-9
J:102925 Li G, et al., Multiple modes of interaction of the deglycosylation enzyme, mouse peptide N-glycanase, with the proteasome. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15809-14
J:172993 Li G, et al., The AAA ATPase p97 links peptide N-glycanase to the endoplasmic reticulum-associated E3 ligase autocrine motility factor receptor. Proc Natl Acad Sci U S A. 2006 May 30;103(22):8348-53
J:188902 Gomes AV, et al., Mapping the murine cardiac 26S proteasome complexes. Circ Res. 2006 Aug 18;99(4):362-71
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89