Sequence Detail

ID/Version

P62482 Q64284 P97381 Q60942 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Voltage-gated potassium channel subunit beta-2; EC=1.1.1.- {ECO:0000250|UniProtKB:P62483};AltName: Full=K(+) channel subunit beta-2;AltName: Full=Kv-beta-2;AltName: Full=Neuroimmune protein F5;

Provider

SWISS-PROT

Sequence

Polypeptide 367 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	53	101	4	13

Sequence references in MGI

J:2307 Cohen JA, et al., Characterization of a novel mRNA expressed by neurons in mature brain. J Neurosci Res. 1992 Feb;31(2):273-84
J:31578 Uebele VN, et al., Functional differences in Kv1.5 currents expressed in mammalian cell lines are due to the presence of endogenous Kv beta 2.1 subunits. J Biol Chem. 1996 Feb 2;271(5):2406-12
J:36040 Fink M, et al., A new K+ channel beta subunit to specifically enhance Kv2.2 (CDRK) expression. J Biol Chem. 1996 Oct 18;271(42):26341-8
J:75891 McCormack K, et al., Genetic analysis of the mammalian K+ channel beta subunit Kvbeta 2 (Kcnab2). J Biol Chem. 2002 Apr 12;277(15):13219-28
J:106453 Connor JX, et al., Genetic modifiers of the Kv beta2-null phenotype in mice. Genes Brain Behav. 2005 Mar;4(2):77-88
J:167856 Perkowski JJ, et al., Deletion of the mouse homolog of KCNAB2, a gene linked to monosomy 1p36, results in associative memory impairments and amygdala hyperexcitability. J Neurosci. 2011 Jan 5;31(1):46-54
J:170684 Vacher H, et al., Cdk-mediated phosphorylation of the Kvbeta2 auxiliary subunit regulates Kv1 channel axonal targeting. J Cell Biol. 2011 Mar 7;192(5):813-24
J:226018 Kole MJ, et al., Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing. J Neurosci. 2015 Aug 12;35(32):11433-44
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87