Sequence Detail

ID/Version

P62746 P01121 Q9CUV7 (UniProt | EBI)

Last sequence update: 1988-08-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Rho-related GTP-binding protein RhoB;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 196 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rhob	ras homolog family member B	55	105	2	7

Sequence references in MGI

J:33389 Reid T, et al., Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain. J Biol Chem. 1996 Jun 7;271(23):13556-60
J:35555 Nakamura T, et al., Cloning of the RhoB gene from the mouse genome and characterization of its promoter region. Biochem Biophys Res Commun. 1996 Sep 24;226(3):688-94
J:71577 Liu AX, et al., Rhob is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells. Mol Cell Biol. 2001 Oct;21(20):6906-12
J:86323 Adini I, et al., RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development. Genes Dev. 2003 Nov 1;17(21):2721-32
J:95631 Westmark CJ, et al., RhoB mRNA is stabilized by HuR after UV light. Oncogene. 2005 Jan 13;24(3):502-11
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114053 Liu Ax, et al., RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6192-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89