Sequence Detail

ID/Version

P62806 A4QMY0 Q5T006 Q9D6Q8 A4FUP8 Q9D0C9 A0AUM5 P02304 Q6PDS7 Q2M2Q5 Q811M0 Q0VDL9 P02305 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Histone H4;

Provider

SWISS-PROT

Sequence

Polypeptide 103 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	H4c1	H4 clustered histone 1	0	102	16	4
Gene	H4c11	H4 clustered histone 11	0	101	16	2
Gene	H4c12	H4 clustered histone 12	0	101	16	2
Gene	H4c14	H4 clustered histone 14	4	104	16	4
Gene	H4c16	H4 histone 16	0	101	17	5
Gene	H4c17	H4 clustered histone 17	0	101	16	2
Gene	H4c2	H4 clustered histone 2	0	101	16	3
Gene	H4c3	H4 clustered histone 3	0	107	16	4
Gene	H4c4	H4 clustered histone 4	0	102	16	2
Gene	H4c6	H4 clustered histone 6	0	101	16	3
Gene	H4c8	H4 clustered histone 8	4	102	16	2
Gene	H4c9	H4 clustered histone 9	0	101	16	5

Sequence references in MGI

J:20236 Meier VS, et al., Nucleotide sequence of two mouse histone H4 genes. Nucleic Acids Res. 1989 Jan 25;17(2):795
J:33128 Seiler-Tuyns A, et al., Structure and expression in L-cells of a cloned H4 histone gene of the mouse. J Mol Biol. 1981 Oct 5;151(4):607-25
J:34962 Wang ZF, et al., Characterization of the mouse histone gene cluster on chromosome 13: 45 histone genes in three patches spread over 1Mb. Genome Res. 1996 Aug;6(8):688-701
J:80094 Marzluff WF, et al., The human and mouse replication-dependent histone genes. Genomics. 2002 Nov;80(5):487-98
J:90491 Schotta G, et al., A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev. 2004 Jun 1;18(11):1251-62
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:109626 Ancelin K, et al., Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. Nat Cell Biol. 2006 Jun;8(6):623-30
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:211428 Southall SM, et al., A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases. Nucleic Acids Res. 2014 Jan;42(1):661-71
J:243518 Goudarzi A, et al., Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters. Mol Cell. 2016 Apr 21;62(2):169-80
J:253015 Xie Z, et al., Metabolic Regulation of Gene Expression by Histone Lysine beta-Hydroxybutyrylation. Mol Cell. 2016 Apr 21;62(2):194-206
J:287408 Zhang D, et al., Metabolic regulation of gene expression by histone lactylation. Nature. 2019 Oct;574(7779):575-580
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:319948 Kelly RDW, et al., Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo. Sci Rep. 2018 Oct 2;8(1):14690