Sequence Detail

ID/Version

P62814 Q3TG74 Q3U791 Q3TL62 Q3UAW7 O09045 P50517 Q3U9Z0 Q3U7C8 Q3TVK6 Q3TWR0 (UniProt | EBI)

Last sequence update: 2004-08-16
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=V-type proton ATPase subunit B, brain isoform; Short=V-ATPase subunit B 2;AltName: Full=Endomembrane proton pump 58 kDa subunit;AltName: Full=Vacuolar proton pump subunit B 2;

Provider

SWISS-PROT

Sequence

Polypeptide 511 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Atp6v1b2	ATPase, H+ transporting, lysosomal V1 subunit B2	25	110	4	8

Sequence references in MGI

J:31176 Laitala-Leinonen T, et al., Resorption-cycle-dependent polarization of mRNAs for different subunits of V-ATPase in bone-resorbing osteoclasts. Mol Biol Cell. 1996 Jan;7(1):129-42
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:101414 Finberg KE, et al., The B1-subunit of the H(+) ATPase is required for maximal urinary acidification. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13616-21
J:169891 Paunescu TG, et al., Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice. Am J Physiol Renal Physiol. 2007 Dec;293(6):F1915-26
J:284463 Frische S, et al., H(+)-ATPase B1 subunit localizes to thick ascending limb and distal convoluted tubule of rodent and human kidney. Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F429-F444
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89