Sequence Detail

ID/Version

P62827 P28746 Q9UDJ5 Q9CSP3 Q9CZA2 Q3U954 Q811M2 Q86V08 Q9CWI7 Q9UEU9 P28747 P17080 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=GTP-binding nuclear protein Ran; EC=3.6.5.- {ECO:0000250|UniProtKB:P62826};AltName: Full=GTPase Ran;AltName: Full=Ras-like protein TC4;AltName: Full=Ras-related nuclear protein;

Provider

SWISS-PROT

Sequence

Polypeptide 216 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ran	RAN, member RAS oncogene family	66	104	3	32

Sequence references in MGI

J:21024 Coutavas EE, et al., Tissue-specific expression of Ran isoforms in the mouse. Mamm Genome. 1994 Oct;5(10):623-8
J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
J:38186 Kang AD, et al., Restoration of lipopolysaccharide-mediated B-cell response after expression of a cDNA encoding a GTP-binding protein. Infect Immun. 1996 Nov;64(11):4612-7
J:57938 Wong PM, et al., Lps(d)/Ran of endotoxin-resistant C3H/HeJ mice is defective in mediating lipopolysaccharide endotoxin responses. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11543-8
J:63595 Steggerda SM, et al., The mammalian Mog1 protein is a guanine nucleotide release factor for Ran. J Biol Chem. 2000 Jul 28;275(30):23175-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:137105 Schulze H, et al., RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules. J Biol Chem. 2008 May 16;283(20):14109-19
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:222250 Shibano T, et al., The Inner Nuclear Membrane Protein Nemp1 Is a New Type of RanGTP-Binding Protein in Eukaryotes. PLoS One. 2015;10(5):e0127271
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89