Sequence Detail

ID/Version

P63034 P97695 O89099 E9QJX3 Q3UP39 (UniProt | EBI)

Last sequence update: 2022-10-12
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Cytohesin-2;AltName: Full=ARF nucleotide-binding site opener; Short=Protein ARNO;AltName: Full=PH, SEC7 and coiled-coil domain-containing protein 2; Short=CLM2;AltName: Full=SEC7 homolog B; Short=mSec7-2;

Provider

SWISS-PROT

Sequence

Polypeptide 400 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cyth2	cytohesin 2	20	98	3	21

Sequence references in MGI

J:49556 Kim HS, et al., Complex regulation of multiple cytohesin-like genes in murine tissues and cells. FEBS Lett. 1998 Aug 21;433(3):312-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:156525 Ikenouchi J, et al., FRMD4A regulates epithelial polarity by connecting Arf6 activation with the PAR complex. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):748-53
J:202589 DiNitto JP, et al., Structural basis and mechanism of autoregulation in 3-phosphoinositide-dependent Grp1 family Arf GTPase exchange factors. Mol Cell. 2007 Nov 30;28(4):569-83
J:202590 Cronin TC, et al., Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains. EMBO J. 2004 Oct 1;23(19):3711-20
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89