Sequence Detail

ID/Version

P63044 Q64357 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Vesicle-associated membrane protein 2; Short=VAMP-2;AltName: Full=Synaptobrevin-2;

Provider

SWISS-PROT

Sequence

Polypeptide 116 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Vamp2	vesicle-associated membrane protein 2	113	115	3	13

Sequence references in MGI

J:96873 Deak F, et al., Synaptobrevin is essential for fast synaptic-vesicle endocytosis. Nat Cell Biol. 2004 Nov;6(11):1102-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:157635 Hager HA, et al., Identification of a novel Bves function: regulation of vesicular transport. EMBO J. 2010 Feb 3;29(3):532-45
J:161112 Ke B, et al., Doc2beta is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis. J Biol Chem. 2007 Jul 27;282(30):21786-97
J:164218 Burre J, et al., Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science. 2010 Sep 24;329(5999):1663-7
J:225407 Fritzius T, et al., WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta. FEBS J. 2007 Mar;274(6):1552-66
J:249825 Park S, et al., UNC-18 and Tomosyn Antagonistically Control Synaptic Vesicle Priming Downstream of UNC-13 in Caenorhabditis elegans. J Neurosci. 2017 Sep 6;37(36):8797-8815
J:266473 Ito H, et al., Sept8 controls the binding of vesicle-associated membrane protein 2 to synaptophysin. J Neurochem. 2009 Feb;108(4):867-80
J:279806 Zulliger R, et al., SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting. PLoS One. 2015;10(9):e0138508
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89