Sequence Detail

ID/Version

P63080 Q3UHR3 P15433 (UniProt | EBI)

Last sequence update: 2004-09-13
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Gamma-aminobutyric acid receptor subunit beta-3 {ECO:0000250|UniProtKB:P28472};AltName: Full=GABA(A) receptor subunit beta-3 {ECO:0000250|UniProtKB:P28472}; Short=GABAAR subunit beta-3 {ECO:0000250|UniProtKB:P28472};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 473 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gabrb3	GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3	78	112	3	30

Sequence references in MGI

J:23743 Kamatchi GL, et al., GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice. Biochim Biophys Acta. 1995 Mar 14;1261(1):134-42
J:39801 Homanics GE, et al., Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):4143-8
J:60491 Ugarte SD, et al., Sensory thresholds and the antinociceptive effects of GABA receptor agonists in mice lacking the beta3 subunit of the GABA(A) receptor. Neuroscience. 2000;95(3):795-806
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:254795 Davenport EC, et al., An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABAA Receptors. Cell Rep. 2017 Oct 3;21(1):70-83
J:281261 Brown LE, et al., gamma-Aminobutyric Acid Type A (GABAA) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains. J Biol Chem. 2016 Jul 1;291(27):13926-42