Sequence Detail

ID/Version

P63318 P05697 (UniProt | EBI)

Last sequence update: 2004-10-11
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Protein kinase C gamma type; Short=PKC-gamma; EC=2.7.11.13;

Provider

SWISS-PROT

Sequence

Polypeptide 697 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prkcg	protein kinase C, gamma	60	122	3	15

Sequence references in MGI

J:3927 Bowers BJ, et al., Isolation and sequence of a mouse brain cDNA coding for protein kinase C-gamma isozyme. Gene. 1993 Jan 30;123(2):263-5
J:16392 Abeliovich A, et al., Modified hippocampal long-term potentiation in PKC gamma-mutant mice. Cell. 1993 Dec 31;75(7):1253-62
J:31211 Chen C, et al., Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice. Cell. 1995 Dec 29;83(7):1233-42
J:43458 Malmberg AB, et al., Preserved acute pain and reduced neuropathic pain in mice lacking PKCgamma [see comments]. Science. 1997 Oct 10;278(5336):279-83
J:103104 Zeitz KP, et al., Reduced development of tolerance to the analgesic effects of morphine and clonidine in PKC gamma mutant mice. Pain. 2001 Dec;94(3):245-53
J:124692 Narita M, et al., Enhanced mu-opioid responses in the spinal cord of mice lacking protein kinase Cgamma isoform. J Biol Chem. 2001 May 4;276(18):15409-14
J:126193 Narita M, et al., Involvement of protein kinase Cgamma isoform in morphine-induced reinforcing effects. Neuroscience. 2001;103(2):309-14
J:127350 Ikeda A, et al., Abnormal features in mutant cerebellar Purkinje cells lacking junctophilins. Biochem Biophys Res Commun. 2007 Nov 23;363(3):835-9
J:175506 Matsumoto S, et al., Isoflurane inhibits protein kinase Cgamma and calcium/calmodulin dependent protein kinase ii-alpha translocation to synaptic membranes in ischemic mice brains. Neurochem Res. 2008 Nov;33(11):2302-9
J:187362 Munton RP, et al., Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics. 2007 Feb;6(2):283-93
J:193126 Zhang L, et al., PKCgamma participates in food entrainment by regulating BMAL1. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):20679-84
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89