ID/Version |
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Sequence description from provider |
RecName: Full=Tubulin alpha-1A chain; EC=3.6.5.- {ECO:0000250|UniProtKB:P68363};AltName: Full=Alpha-tubulin 1;AltName: Full=Alpha-tubulin isotype M-alpha-1;AltName: Full=Tubulin alpha-1 chain;Contains: RecName: Full=Detyrosinated tubulin alpha-1A | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
451
aa
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Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:19085
Lewis SA, et al., Five mouse tubulin isotypes and their regulated expression during development. J Cell Biol. 1985 Sep;101(3):852-61
J:25928 Villasante A, et al., Six mouse alpha-tubulin mRNAs encode five distinct isotypes: testis-specific expression of two sister genes. Mol Cell Biol. 1986 Jul;6(7):2409-19 J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:112743 Peris L, et al., Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends. J Cell Biol. 2006 Sep 11;174(6):839-49 J:150280 Rogowski K, et al., Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation. Cell. 2009 Jun 12;137(6):1076-87 J:150408 Peris L, et al., Motor-dependent microtubule disassembly driven by tubulin tyrosination. J Cell Biol. 2009 Jun 29;185(7):1159-66 J:201638 Bosch Grau M, et al., Tubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal cilia. J Cell Biol. 2013 Aug 5;202(3):441-51 J:227641 Kerr JP, et al., Detyrosinated microtubules modulate mechanotransduction in heart and skeletal muscle. Nat Commun. 2015;6:8526 J:241131 Janke C, et al., Tubulin polyglutamylase enzymes are members of the TTL domain protein family. Science. 2005 Jun 17;308(5729):1758-62 J:272424 Aillaud C, et al., Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation. Science. 2017 Dec 15;358(6369):1448-1453 J:300009 Gadadhar S, et al., Tubulin glycylation controls axonemal dynein activity, flagellar beat, and male fertility. Science. 2021 Jan 8;371(6525) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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