Sequence Detail

ID/Version

P70122 Q3TG78 Q9CR18 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Ribosome maturation protein SBDS;AltName: Full=Protein 22A3;AltName: Full=Shwachman-Bodian-Diamond syndrome protein homolog;

Provider

SWISS-PROT

Sequence

Polypeptide 250 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sbds	SBDS ribosome maturation factor	32	103	3	28

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:112167 Zhang S, et al., Loss of the mouse ortholog of the shwachman-diamond syndrome gene (Sbds) results in early embryonic lethality. Mol Cell Biol. 2006 Sep;26(17):6656-63
J:152330 Ball HL, et al., Shwachman-Bodian Diamond syndrome is a multi-functional protein implicated in cellular stress responses. Hum Mol Genet. 2009 Oct 1;18(19):3684-95
J:171416 Finch AJ, et al., Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Genes Dev. 2011 May 1;25(9):917-29
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89