Sequence Detail

ID/Version

P70327 B2RU37 Q5SDA2 (UniProt | EBI)

Last sequence update: 2012-05-16
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=T-box transcription factor TBX6; Short=T-box protein 6;

Provider

SWISS-PROT

Sequence

Polypeptide 436 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tbx6	T-box 6	27	145	4	21

Sequence references in MGI

J:35709 Agulnik SI, et al., Evolution of mouse T-box genes by tandem duplication and cluster dispersion. Genetics. 1996 Sep;144(1):249-54
J:37336 Chapman DL, et al., Tbx6, a mouse T-Box gene implicated in paraxial mesoderm formation at gastrulation. Dev Biol. 1996 Dec 15;180(2):534-42
J:80954 Chapman DL, et al., Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6. Nature. 1998 Feb 12;391(6668):695-7
J:93881 Hofmann M, et al., WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos. Genes Dev. 2004 Nov 15;18(22):2712-7
J:137163 Hadjantonakis AK, et al., Tbx6 regulates left/right patterning in mouse embryos through effects on nodal cilia and perinodal signaling. PLoS One. 2008;3(6):e2511
J:217059 Takemoto T, et al., Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells. Nature. 2011 Feb 17;470(7334):394-8